Amorphous and co-amorphous olanzapine stability in formulations intended for wet granulation and pelletization

HIGHLIGHTS

  • who: Nuno F. da Costa and collaborators from the iMedULisboa-Research Institute for Medicines, Faculdade Farmu00e1cia, Universidade Lisboa, Tuebingen, Germany have published the Article: Amorphous and Co-Amorphous Olanzapine Stability in Formulations Intended for Wet Granulation and Pelletization, in the Journal: (JOURNAL) of 28/07/2022
  • how: The results indicated that OLZ was reconverted back to a crystalline state after exposure to water and heat conversely OLZ-CAMs stabilized with saccharin (SAC) a sulfonic acid did not show any significant loss of the content confirming the higher stability of OLZ in the CAM. In this . . .

     

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