Amp-activated protein kinase — a journey from 1 to 100 downstream targets

HIGHLIGHTS

  • who: D. Grahame Hardie from the DivisionUniversity of have published the Article: AMP-activated protein kinase u2014 a journey from 1 to 100 downstream targets, in the Journal: (JOURNAL) of 16/Nov/2022
  • what: This model had the huge advantage that Doreen had shown that developing T_cells in the thymus express only the u03b11 isoform of AMPK , so that it was not necessary to knock out u03b12 as well. The contribution to the resulting paper was to confirm that the caspase-3 cleavage, when conducted in cell-free assays, did not affect the stability of . . .

     

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