Amphipathic dendritic poly-peptides carrier to deliver antisense oligonucleotides against multi-drug resistant bacteria in vitro and in vivo

HIGHLIGHTS

• who: Zhou Chen from the Department of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xiu2019an, Shaanxi, China have published the research: Amphipathic dendritic poly-peptides carrier to deliver antisense oligonucleotides against multi-drug resistant bacteria in vitro and in vivo, in the Journal: (JOURNAL)
• what: We designed a series of DPPs with different hydrophobicity, positive charge distribution pattern and amino_acid types, and prepared a novel type of DP-AD noncovalently.
• how: For the first time the authors designed DPP as a potent carrier to deliver ASOs for combating MDR bacteria and demonstrated . . .
  

   

  

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