An active form of sphingosine kinase-1 is released in the extracellular medium as component of membrane vesicles shed by two human tumor cell lines

HIGHLIGHTS

• who: Salvatrice Rigogliuso and collaborators from the di Biologia Cellulare e dello Sviluppo, Università di Palermo, Viale delle, Scienze ed16, Palermo, Italy have published the Article: An Active Form of Sphingosine Kinase-1 Is Released in the Extracellular Medium as Component of Membrane Vesicles Shed by Two Human Tumor Cell Lines, in the Journal: (JOURNAL) of 16/Nov/2009
• what: The authors investigated whether vesicles shed by hepatocarcinoma and carcinoma cultured cells contain S1P-generating enzymes. The data from this research shows that neutral ceramidase (nCDase) and SphK1 are localized in vesicles, supporting the view . . .
  

   

  

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