An antagomir to microrna let7f promotes neuroprotection in an ischemic stroke model

HIGHLIGHTS

• who: Amutha Selvamani and colleagues from the Editor: Josef Priller, Charité-Universitätsmedizin Berlin, Germany have published the paper: An Antagomir to MicroRNA Let7f Promotes Neuroprotection in an Ischemic Stroke Model, in the Journal: (JOURNAL) of February/29,/2012
• what: The authors report that two conserved IGF pathway regulatory microRNAs Let7f and miR1 can be inhibited to mimic and even extend the neuroprotection afforded by IGF-1. The studies show that IGF-1 is neuroprotective to middle aged females even when administered 4 h post stroke making this an attractive candidate for stroke therapy. In . . .
  

   

  

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