An asparagine metabolism-based classification reveals the metabolic and immune heterogeneity of hepatocellular carcinoma

HIGHLIGHTS

  • who: Jianguo Bai from the The RNA-sequencing expression profiles and corresponding overall survival (OS) and disease-free survival (DFS) data of HCC were acquired from the Cancer Genome Atlas (TCGA), International Cancer Genome Consortium (ICGC) database and , dataset in the Gene Expression Omnibus (GEO) database [26-29]A total of , HCC patients was retrieved from the TCGA database. The inclusion criteria of TCGA were patients that were diagnosed with HCC, and had not received prior treatment for their disease (ablation, chemotherapy, or radiotherapy). Also, primary HCC cases contributed by Institute of Physical and Chemical Research (RIKEN . . .

     

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