An atlas of endogenous dna double-strand breaks arising during human neural cell fate determination

HIGHLIGHTS

• who: Roberto Ballarino from the DepartmentNEU have published the research work: An atlas of endogenous DNA double-strand breaks arising during human neural cell fate determination, in the Journal: (JOURNAL)
• what: The authors show that genome-wide maps of endogenous DSBs are highly correlated between experimental replicates up to 10 kilobases (kb) resolution and that DSBs are non-uniformly distributed along the genome in all three cell differentiation stages analyzed. The authors provide sBLISS13 14 RNA-Seq13 and Hi-C13 datasets from multiple experimental replicates for each differentiation stage (see Supplementary Table 1 for a . . .
  

   

  

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