An efficient kinetic model for assemblies of amyloid fibrils and its application to polyglutamine aggregation

HIGHLIGHTS

  • who: Stéphanie Prigent et al. from the Editor: Yoshitaka Nagai, National Center of Neurology and Psychiatry, Japan have published the research work: An Efficient Kinetic Model for Assemblies of Amyloid Fibrils and Its Application to Polyglutamine Aggregation, in the Journal: PLOS ONE | www.plosone.org of November/13,/2012
  • what: The authors propose a novel and efficient analytical method capable of modelling and simulating amyloid aggregation processes. The model demonstrates the existence of a monomeric structural intermediate ~c1 acting as a nucleus and deriving from a non polymerizing monomer (c1 ). The authors propose here . . .

     

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