An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the tlr7/irf-7 pathway as a proof of concept

HIGHLIGHTS

• who: Nikaïa Smith from the Laboratoire Paris Descartes, Sorbonne Paris Cité, Paris, France have published the Article: An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept, in the Journal: Scientific Reports Scientific Reports
• what: The authors provide some direct demonstration that TLR7 is required for the sensing of HIV or influenza virus particles by primary human pDC.
• how: As control for transfection the authors used a siRNA targeting cyclophilin B that is labeled with the fluorescent dye . . .
  

   

  

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