An emerin lem-domain mutation impairs cell response to mechanical stress

HIGHLIGHTS

• who: Nada Essawy and collaborators from the Laboratory of Structural Biology and Radiobiology, Institute for Integrative Biology of the Cell (CEA, CNRS, University Paris South), University Paris-Saclay, Gif-sur-Yvette, France have published the research work: An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress, in the Journal: Cells 2019, 8, 570 of /2019/
• what: From all these data, the authors propose that the LEM-domain mutations impact emerin self-assembly and cause emerin degradation in cells. That being the case, the availability of myofibroblasts expressing each of the emerin LEM-domain . . .
  

   

  

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