An ex vivo test to investigate genetic factors conferring susceptibility to atypical haemolytic uremic syndrome

HIGHLIGHTS

  • who: Sara Gastoldi and collaborators from the University of Toronto, Canada have published the article: An ex vivo test to investigate genetic factors conferring susceptibility to atypical haemolytic uremic syndrome, in the Journal: (JOURNAL)
  • what: As further check of good reproducibility of the assay, in this study the authors performed biological replicates by analysing samples collected at 2 different time points in remission from 6 aHUS patients. By studying 223 subjects who belong to 60 aHUS pedigrees, here the authors show that the ex vivo assay based on serum-induced C5b-9 formation on activated . . .

     

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