An explorative study into the aetiology of developmental dysplasia of the hip using targeted urine metabolomics

HIGHLIGHTS

  • who: Amanda M. L. Rhodes and colleagues from the University Hospital, YD, UK have published the Article: An Explorative Study into the Aetiology of Developmental Dysplasia of the Hip Using Targeted Urine Metabolomics, in the Journal: Antioxidants 2023, 12, 538. of 21/Dec/2022
  • what: This investigation shows the power of metabolomics and highlights the importance of normalisation for hydration status to disentangle developmental disorders.
  • how: This colourimetric method is based on the reaction of malondialdehyde (MDA) and related reactive aldehydes generated from the ROS-induced breakdown of unsaturated lipids/fatty_acids with thiobarbituric . . .

     

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