An fgfr1-spry2 signaling axis limits basal cell proliferation in the steady-state airway epithelium

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• who: Gayan I. Balasooriya from the Stem Cell Institute University of Cambridge , QN, UK have published the article: An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium, in the Journal: (JOURNAL) of July/21,/2015
• what: The authors show that airway basal cells is post-translationally modified response to This allows to inhibit intracellular downstream of other receptor tyrosine kinases and restrain basal cell proliferation. has previously been characterized cell lines vitro. The authors demonstrate that in airway BCs, SPRY2 is post-translationally modified downstream of FGFR1, allowing SPRY2 . . .
  

   

  

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