An in silico model of t cell in fi ltration dynamics based on an advanced in vitro system to enhance preclinical decision making in cancer immunotherapy

HIGHLIGHTS

  • who: Immunotherapy and collaborators from the Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland University of Montreal, Canada have published the research work: An in silico Model of T Cell In fi ltration Dynamics Based on an Advanced in vitro System to Enhance Preclinical Decision Making in Cancer Immunotherapy, in the Journal: (JOURNAL)
  • what: The authors propose a reaction-diffusion-chemotaxis system of partial differential equations (PDEs) to describe the evolution of a continuous PBMC density. The authors focus on capturing the dynamics of infiltrating PBMCs and thus consider a domain including . . .

     

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