An in vitro model to investigate the potential of solid dispersions to form pharmacobezoars

HIGHLIGHTS

  • who: Hannes Gierke and collaborators from the Department of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany have published the Article: An In Vitro Model to Investigate the Potential of Solid Dispersions to Form Pharmacobezoars, in the Journal: Pharmaceutics 2022, 14, 2608. of /2022/
  • what: To isolate individual syringes in the model, the authors developed a construction where plunger.
  • how: To verify that the pharmacobezoar formation potential can be assessed based on the observed agglomeration potential the authors conducted a sequence of experiments with two HPMC . . .

     

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