HIGHLIGHTS
- What: The study showed that and biodegradable frozen Pol/T hydrogels to induce local hypothermia in TBI mice can be used for the treatment of traumatic brain injury. In this study, the cytotoxicity of the Pol hydrogel was determined by the MTT assay. The studies showed that the local hypothermia induced by the Pol/T hydrogel attenuated the expression of proinflammatory factors and restrained the activation of microglia and astrocytes.
- Who: Yuhan Han from the The human study was approved by the Ethics Committee of the Affiliated Hospital of Xuzhou Medical University (XYFY2020-KL208-01 . . .
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