An insulator blocks access to enhancers by an illegitimate promoter, preventing repression by transcriptional interference

HIGHLIGHTS

  • who: Miki Fujioka and collaborators from the Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America have published the article: An insulator blocks access to enhancers by an illegitimate promoter, preventing repression by transcriptional interference, in the Journal: (JOURNAL) of April/26,/2021
  • what: The authors describe how insulators can prevent repression of one gene by preventing inappropriate transcription of another gene without blocking read-through of transcription per se. The authors focus on the two insulators that flank the eve locus, homie and nhomie . The authors show that the stripe imbalance seen at the . . .

     

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