An integrin axis induces ifn- production in plasmacytoid dendritic cells

HIGHLIGHTS

• who: Davina Camargo Madeira Simoes and colleagues from the Immunology Laboratory of Vily Panoutsakopoulou, Center for Basic Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece have published the Article: An integrin axis induces IFN- production in plasmacytoid dendritic cells, in the Journal: (JOURNAL) of 12/03/2023
• what: The authors demonstrate that sOpn enhances this steady-state expression of IFN-u03b2 in pDCs, possibly promoting an alert mechanism against pathogenic antigens. Under endotoxin-free conditions and in the absence of PAMPs, the authors demonstrate that ligation of u03b14-integrin by the SLAYGLR . . .
  

   

  

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