HIGHLIGHTS
- who: Kevin A. Robertson and collaborators from the Division of Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom, SynthSys at have published the Article: An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway, in the Journal: (JOURNAL)
- what: The authors show that miR-342-5p does this through a multihit strategy turning down the master regulator of sterol biosynthesis as well as several specifically targeted enzymes within the pathway. On the basis of these observations, combined with evidence from the metabolic rescue experiments, the authors . . .
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