An isogenic cell line panel for sequence-based screening of targeted anticancer drugs

HIGHLIGHTS

• who: Ashley L. Cook from the Center for CancerHopkins University Baltimore, MD, USA have published the paper: An isogenic cell line panel for sequence-based screening of targeted anticancer drugs, in the Journal: (JOURNAL) of June/17,/2022
• what: The authors focused on 22 pathways that were collectively altered in greater than two-thirds of the cancers as assessed in multiple large scale sequencing efforts .
• how: For this screen the authors used 81 cell lines derived from two different parental cell lines and representing 19 targeted pathways . To model the power of the . . .
  

   

  

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