HIGHLIGHTS
- who: Natalwala et_al and colleagues from the Hanyang University, South Korea United States have published the article: An Isogenic Collection of Pluripotent Stem Cell Lines With Elevated u03b1 -Synuclein Expression Validated for Neural Induction and Cortical Neuron Differentiation, in the Journal: (JOURNAL)
- what: The authors aimed to generate an isogenic collection of hESC lines with differing levels of u03b1Syn expression and use this to systematically investigate if elevated u03b1Syn expression affects cortical neuron differentiation. Across multiple clonal lines, multiple rounds of cortical neuron differentiation using two robust differentiation protocols and unbiased transcriptomic analysis, the authors . . .
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