An iterative workflow for mining the human intestinal metaproteome

HIGHLIGHTS

  • who: Rooijers et_al BMC Genomics et al. from the (UNIVERSITY) have published the paper: An iterative workflow for mining the human intestinal metaproteome, in the Journal: (JOURNAL)
  • what: This approach has shown that most of the intestinal phylotypes belong to a limited set of phyla, including the Firmicutes, Bacteroidetes, Actinobacteria, Proteobacteria and Verrucomicrobia . Since both approaches suffer from unacceptable highfalse positive rates, which lead to low accuracy in the identification of proteins, the authors aimed to develop an iterative workflow based on a synthetic metagenome from over 200 intestinal species that would increase the sensitivity . . .

     

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