An olive-derived elenolic acid stimulates hormone release from l-cells and exerts potent beneficial metabolic effects in obese diabetic mice

HIGHLIGHTS

  • who: Dongmin Liu and Bin Xu from the The University of Tennessee, Knoxville, United States have published the research: An olive-derived elenolic acid stimulates hormone release from L-cells and exerts potent beneficial metabolic effects in obese diabetic mice, in the Journal: (JOURNAL)
  • what: The authors generated EA by hydrolyzing oleuropein and investigated the effects of EA on GLP-1 and PYY secretion in L-cells and further explored the underlying mechanism of EA`s action. The authors show that EA is an incretin secretagogue, with 1-10 u00b5M concentration inducing significant GLP-1 . . .

     

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