An optimized factor h-fc fusion protein against multidrug-resistant neisseria gonorrhoeae

HIGHLIGHTS

  • who: Jutamas Shaughnessy and colleagues from the Boston University, United States have published the Article: An optimized Factor H-Fc fusion protein against multidrug-resistant Neisseria gonorrhoeae, in the Journal: (JOURNAL)
  • what: Collectively, this study provides compelling evidence for increased PorB1B strain coverage with the optimized Fc3/FH* molecule. The authors show that Fc3/FH* retains its activity in_vitro after lyophilization, an important step in its development as an IVR-delivered drug.
  • how: Data were acquired on a BD LSR II flow cytometer and data were analyzed using FlowJo software. Using C6-/- mice . . .

     

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