An orthotopic model of glioblastoma is resistant to radiodynamic therapy with 5-aminolevulinic acid

HIGHLIGHTS

  • who: Charles Dupin and collaborators from the (BoRdeaux Institute of onCology), UMR1312, University of Bordeaux, Bordeaux, France have published the paper: An Orthotopic Model of Glioblastoma Is Resistant to Radiodynamic Therapy with 5-AminoLevulinic Acid, in the Journal: Cancers 2022, 14,gests 4244 of /2022/
  • what: The study shows for the first time that in a preclinical tumor model relevant to human glioblastoma treated as in clinical routine 5-ALA administration although leading to important accumulation of PpIX does not potentiate radiotherapy. The aim of this work was to establish a robust preclinical patient-derived . . .

     

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