HIGHLIGHTS
- who: Yuhao Zhao from the Department of Surgery, Renji Hospital Affiliated to Jiao Tong University School of Medicine, Jiao Tong University School of Medicine, China have published the research: An Overview of Epigenetic Methylation in Pancreatic Cancer Progression, in the Journal: (JOURNAL)
SUMMARY
Aberrant methylation of CpG islands in the promoter leads to downregulation of a variety of gene_expression through the interaction with methylation-binding proteins. Abnormal DNA methylation (hypermethylation and hypomethylation), mainly in CpG islands, is closely related to tumor development including PC. Growing evidence has revealed on the specific mechanisms of . . .
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