HIGHLIGHTS
- who: Posted Date October and colleagues from the Chinese Academy of Medical Sciences and Peking Union Medical College Tsinghua University have published the research: An ultra-small bispeciufffdc protein augments tumor penetration and treatment for pancreatic cancer, in the Journal: (JOURNAL)
- what: We constructed the bispecific fusion_protein Bi-fp50 that could simultaneously target both EGFR and VEGF of PDAC cells.
SUMMARY
The synthesized Bi-fp50 agent showed excellent bispecific targeting for VEGF and EGFR and synergistic anticancer activity for PDACs in_vitro. The antiVEGF function of Bi-fp50 could normalize tumor vasculature . . .
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