HIGHLIGHTS
- who: Farhad Pouremamali from the Digestive Diseases Research Center, Ardabil University of Medical Sciences, Ardabil, Iran have published the article: An update of Nrf2 activators and inhibitors in cancer prevention/promotion, in the Journal: (JOURNAL)
- what: Since Nrf2 has paradoxical roles in cancer biology, it is essential to understand the molecular mechanisms leading to tumor suppressor or oncogenic effects of Nrf2.
- future: Studies should be conducted to find cancer targeting drug candidates with good pharmacodynamic/ pharmacokinetic parameters for human cancer.
SUMMARY
Several studies have provided evidence that preventing the . . .
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