Analysis of early childhood intestinal microbial dynamics in a continuous-flow bioreactor

HIGHLIGHTS

  • What: The authors report the reproducible longitudinal dynamics of early-life communities cultured in an advanced model of the human gut providing an experimental approach and a characterized resource to support future investigations of the human gut microbiota in early childhood. To demonstrate the efficiency of this chemostat model to emulate the early life gut microbiota, the study focuses on three key points: generalizability of the data for early childhood gut microbiota, taxonomic representativeness of organisms supported by the chemostat model, and_(3) reproducibility capacity of the model to produce similar communities from the same inoculum. The . . .

     

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