Analysis of gastric microbiota and helicobacter pylori infection in gastroesophageal reflux disease

HIGHLIGHTS

• who: Titong Sugihartono from the upper-endoscopy evaluationIn the beginning, all patients with H. pylori positive were classified as gastritis group. The patients presented with reflux symptoms and mucosal lesion (esophageal erosions), which fulfilled the Los Angeles classification were diagnosed with ERD. If the patients presented with reflux symptoms without any mucosal lession (esophageal erosions), NERD was diagnosed. We included subjects without reflux symptoms and no intestinal metaplasia or atrophy score of more than , (mild) for histology evaluation in the gastritis group. Randomization was performed to obtain , samples for ERD, NERD and gastritis for sequencing. We included . . .
  

   

  

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