Analysis of mutational profile of hypopharyngeal and laryngeal head and neck squamous cell carcinomas identifies kmt2c as a potential tumor suppressor

HIGHLIGHTS

  • who: Marcin M. Machnicki et al. from the Medical University of Graz, Austria have published the article: Analysis of Mutational Profile of Hypopharyngeal and Laryngeal Head and Neck Squamous Cell Carcinomas Identifies KMT2C as a Potential Tumor Suppressor, in the Journal: (JOURNAL)
  • what: The study has limitations that warrant further research. The authors provide a new insight into the molecular landscape of hypopharyngeal cancer and identify potential new biomarkers.
  • how: This data was also segmented using CNVkit built-in cbs method after exclusion of homozygous variants to aid in identification of regions with . . .

     

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