Analysis of mutational variations in tp53 tumour suppressor gene among pakistani head and neck cancer patients

HIGHLIGHTS

  • What: The aim of this study was to determine if HNC patients from the Southern Punjab area had any mutations in the TP53 gene exon 5-8. The authors compared demographic factors and non-demographic factors between cases and controls. In the current study, all exon sequence chromatograms showed heterozygous mutations similar to the study of Leng et al and contrary to the study of Baugh et al which reported homosygous mutations in 50% to 60% of human cancer.
  • Who: TP et al. from the Department of Zoology, The Women University Multan, Multan, Pakistan have . . .

     

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