Analysis of nucleotide insertion opposite urea and translesion synthesis across urea by dna polymerases

HIGHLIGHTS

  • who: Taishu Kawada from the (UNIVERSITY) have published the research: Analysis of nucleotide insertion opposite urea and translesion synthesis across urea by DNA polymerases, in the Journal: (JOURNAL)
  • what: DNA_polymerases u03b1, u03b4, u03b6, and Kf exo- predominantly inserted dATP opposite Ua, whereas DNA_polymerase u03b7 inserted dCTP, dGTP, dATP and dTTP.

SUMMARY

    The authors describe the studies of nucleotide incorporations and translesion synthesis in relation to Ua with DNA_polymerases α, δ, ε, η, ζ and Dpo4. The authors confirmed nucleotide incorporation and extension in relation to Ua using Kf exo- and DNA_polymerase β. Calf thymus DNA_polymerase α and human . . .

     

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