HIGHLIGHTS
- who: Erlandson Karl J. from the (UNIVERSITY) have published the paper: Analysis of Polypeptide Movement in the SecY Channel during SecA-mediated Protein Translocation*, in the Journal: (JOURNAL) of December/19,/2007
SUMMARY
One possibility is that SecA and the channel bind the polypeptide chain in an alternating manner; when SecA pushes the polypeptide, the channel would allow free movement, whereas when SecA resets, the channel would hold on to the polypeptide and prevent it from sliding back into the cytosol. In all these models the polypeptide would be moved by "two hands . . .
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