Analysis of s gene characteristic sequences and changes in properties of protein expression in hbv ascs with low-level hbsag

HIGHLIGHTS

SUMMARY

    Unlike occult hepatitis infection, the mechanism of chronic HBV infection with persistent low-level HBsAg expression and occult hepatitis infection partially intersect, but the low-level HBsAg population can detect the low concentration of HBsAg in the host serum, accompanied by low or no replication of HBV DNA, while the occult hepatitis infected people show negative HBsAg detection and positive HBV DNA. The authors speculated that the formation of HBsAg-CIC may be the process of active elimination of HBV ability of effectively clearing HBsAg CIC decreased which led to the accumulation of HBsAg . . .

     

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