HIGHLIGHTS
- who: Min-Chang Kim and Young-Joo Lee from the Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Kyungheedae-ro, Dongdaemungu, Seoul, Republic of Korea have published the Article: Analysis of Time-Dependent Pharmacokinetics Using In Vitro-In Vivo Extrapolation and Physiologically Based Pharmacokinetic Modeling, in the Journal: Pharmaceutics 2022, 14, 2562. of 22/Nov/2022
- what: This study shows the TDPK after repeated dosing by hepatic uptake induction not hepatic metabolism as well as the effectiveness of an ex approach combined with IVIVE and PBPK modeling to investigate the TDPK.
SUMMARY . . .
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