Anatomy and function of the vertebral column lymphatic network in mice

HIGHLIGHTS

• who: Laurent Jacob from the Université Yale University France have published the paper: Anatomy and function of the vertebral column lymphatic network in mice, in the Journal: Neurology,
• what: The authors report that vertebral lymphatics are predominantly localized in the epidural space above the dura mater and drain tracers injected into the thoraco-lumbar spinal cord toward thoracic mediastinal lymph nodes. The authors show that VEGF-C-induced vertebral lymphangiogenesis exacerbates immune-cell infiltration and cytotoxic demyelination of spinal cord lesions in the lysolecithin (LPC)-induced focal demyelination model21. To conclude, this study shows that . . .
  

   

  

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