Ancestral stem cell reprogramming genes active in hemichordate regeneration

HIGHLIGHTS

• who: Kuni Tagawa from the Institute for Biogenesis Research, University of Hawai‘i at Mānoa, Honolulu, HI, United States, Marine Biological have published the research work: Ancestral Stem Cell Reprogramming Genes Active in Hemichordate Regeneration, in the Journal: (JOURNAL)
• what: The authors show that hemichordates, kin to chordates, carry functional homologs of key genes in the mammalian reprogramming factor gene network and express these genes during regeneration. The authors showed that Pf-Pou3 could replace the function of intrinsic mouse Oct4 in ES cells.

SUMMARY

The robust regeneration capacity of . . .

 



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