Anchoring geometry is a significant factor in determining the direction of kinesin-14 motility on microtubules

HIGHLIGHTS

• who: Masahiko Yamagishi from the DepartmentThe University Japan have published the research: Anchoring geometry is a significant factor in determining the direction of kinesin-14 motility on microtubules, in the Journal: Scientific Reports Scientific Reports
• how: To clarify the role of the Ncd neck-mimic the authors examined the directionality of a C-terminal anchored Ncd-kinesin-1 chimera nKn664-BP which contains the kinesin-1 catalytic core with Ncd neck-helix and neck-mimic (Fig 1b). This result is consistent with the kinesin motor domain having a lateral component of movement with the same . . .
  

   

  

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