And differentiation potential of airway basal cells

HIGHLIGHTS

  • who: Krt and colleagues from the DepartmentUniversity of of Medicine, Iowa City, Iowa, USA have published the research work: and differentiation potential of airway basal cells, in the Journal: (JOURNAL)
  • what: This work shows that and functionally regulate BC behavior which is relevant in chronic disease states like BO. The authors show that Krt14 and Krt15 expression dynamics have a functional impact on BC behavior (namely, proliferation, maintenance, and differentiation). The authors demonstrate that disruption of Krt14 and Krt15 in mouse airway BCs leads to opposite phenotypes. Last, the authors show that the phenotype observed . . .

     

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