And subsequent antitumor t_cell response in prostate cancer

HIGHLIGHTS

  • who: UBC and colleagues from the DepartmentHuazhong University, Wuhan, China have published the research: and subsequent antitumor T_cell response in prostate cancer, in the Journal: (JOURNAL)
  • what: The authors report that PCa growth in mice with macrophage-specific is substantially suppressed compared with that in wild-type littermates an effect partially ascribed to the augmented CD8+ T cell response. To investigate the clinical relevance of SUMOylation in PCa, the authors focused on UBC9, the most critical SUMO E2 conjugating enzyme, and queried a series of expression and survival data sets of PCa patients. In this . . .

     

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