Androgen receptor signaling and spatial chromatin organization in castration-resistant prostate cancer

HIGHLIGHTS

  • who: Qin Feng from the United States Tulane University, United States have published the research work: Androgen receptor signaling and spatial chromatin organization in castration-resistant prostate cancer, in the Journal: (JOURNAL)
  • what: The studies discussed in this review represent early steps toward understanding how the higher order of genomic organization affects the development of CRPC, yet more questions need to be addressed in future studies.

SUMMARY

    Although it was initially believed that these resistant tumors are no longer dependent on the AR signaling, later studies have demonstrated that majority of . . .

     

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