Angiotensin ii receptor blocker irbesartan enhanced sirt1 longevity signaling replaces the mitochondrial biogenetic survival pathway to attenuate hypertension-induced heart apoptosis

HIGHLIGHTS

• who: Pei-Ying Pai and colleagues from the Division of Cardiology, Department of Internal Medicine, China Medical University and Hospital have published the paper: Angiotensin II Receptor Blocker Irbesartan Enhanced SIRT1 longevity Signaling Replaces the Mitochondrial Biogenetic Survival Pathway to Attenuate Hypertension-Induced Heart Apoptosis, in the Journal: (JOURNAL)
• what: This study investigated whether type 1 (ARB) and partial agonist of PPAR-γ prevents by suppressing cardiac Fas/FasL-mediated to mitochondria-mediated in the hearts of hypertensive rat model. blotting were measured in the excised hearts from three groups i.e. an untreated hypertensive group . . .
  

   

  

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