Angiotensin ii type 2 receptor blockade increases bone mass*

HIGHLIGHTS

• who: Yayoi Izu from the EXPERIMENTAL PROCEDURES Animals-9-Week-old C BL/ J male mice were purchased from Oriental Yeast Co(Tokyo, Japan). Angiotensin II type , receptor-deficient mice were generated on a C BL/, background as described previously (23). The mice were kindly gifted from Dr. Tadashi Inagami, Vanderbilt University School of Medicine. We used, week-old male mice. All experiments were conducted according to the guidelines from the Animal Welfare Committee of Tokyo Medical and Dental University. Histochemistry for Tartrate-resistant Acid Phosphatase (TRAP)-The animals were deeply anesthetized with ether and perfused through . . .
  

   

  

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