HIGHLIGHTS
- who: Ankyrin-B and collaborators from the University of Glasgow, United Kingdom have published the research: Ankyrin-B is lipid-modi ed by S -palmitoylation to promote dendritic membrane scaffolding of voltage-gated sodium channel 1.2 in neurons, in the Journal: (JOURNAL)
- what: The authors show that ankyrin-B is capable of being palmitoylated by zDHHC17 in heterologous cells and further validated those findings by demonstrating zDHHC17 is a critical mediator of endogenous ankyrin-B palmitoylation in neurons. While ankyrin-G is palmitoylated by zDHHC5 and zDHHC8 at one cysteine site Cys70 (He et_al . . .
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