HIGHLIGHTS
- who: TYPE and colleagues from the University of Mu00fcnster, Germany have published the article: Annexin A2 and Kidney Diseases, in the Journal: (JOURNAL)
- what: The studies have shown that tPA, a ligand of ANXA2, promotes kidney fibrosis and inflammation in the mice with unilateral ureteral obstruction (UUO), a classic chronic kidney disease mouse model.
SUMMARY
Annexins are a family of different calcium-regulated phospholipids-binding proteins, which were named for their ability to "annex" meaning aggregate membranes (Creutz et_al, 1978; Bharadwaj et_al, 2013; Luo and Hajjar, 2013). Each repeat sequence is . . .
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