Anti-angptl3-fld monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage

HIGHLIGHTS

  • who: Qianying Lv from the Mouse model Animal experiments were approved by the Animal Ethics Committee of the Children`s Hospital of Fudan University (NO2020_235) and conducted in accordance with the recommendations of the Guidelines for Ethical Conduct in the Care and Use of Animals. BALB/c mice (6, weeks old) were obtained from Shanghai SLAC Laboratory Animal Co [, ]. Ltd. All the mice had access to water and food ad libitum, and were randomly divided into the control (ctrl) group, E , mAb (mAb) group, adriamycin nephropathy (ADR) group, ADR + mAb group, and the non-specific IgG group . . .

     

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