Anti-d4gdi antibodies activate platelets in vitro: a possible link with thrombocytopenia in primary antiphospholipid syndrome

HIGHLIGHTS

  • who: C. Barbati from the Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Viale del Policlinico, Rome, Italy have published the article: Anti-D4GDI antibodies activate platelets in vitro: a possible link with thrombocytopenia in primary antiphospholipid syndrome, in the Journal: (JOURNAL)
  • what: The authors show here that antibodies anti-D4GDI are present in the sera of PAPS patients and can prime platelet activation explaining at least in part the pro-thrombotic state and the thrombocytopenia of PAPS patients. Thrombocytopenia is the most common hematological feature of patients with antiphospholipid syndrome , and . . .

     

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