Anti-gb3 monoclonal antibody inhibits angiogenesis and tumor development

HIGHLIGHTS

  • who: Anti-Gb et al. from the France France France have published the paper: Anti-Gb3 Monoclonal Antibody Inhibits Angiogenesis and Tumor Development, in the Journal: PLOS ONE | www.plosone.org of November/26,/2012
  • what: The authors explore the anti-angiogenic therapeutic advantage of a tumor immunotherapy targeting the globotriaosylceramide The authors demonstrate that 3E2 endothelial cell proliferation in vitro by slowing endothelial cell proliferation and by increasing mitosis duration. The study demonstrates that is a viable alternative target for immunotherapy and inhibition. The authors demonstrate that Gb3 is overexpressed in proliferating endothelial cells . . .

     

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