HIGHLIGHTS
- who: Anahita Shahraz from the InstitutUniversity Hospital Bonn, Bonn, Germany have published the paper: Anti-inflammatory activity of low molecular weight polysialic acid on human macrophages, in the Journal: Scientific Reports Scientific Reports
- what: The authors show that low molecular weight polySia (avDP20) acted anti-inflammatory on human THP1 macrophages by inhibiting the LPS-induced gene transcription and protein secretion of TNFSF2 and by preventing the oxidative burst associated with phagocytosis of debris or fibrillary amyloid-β 1-42. The authors demonstrate that the anti-inflammatory effect of polySia avDP20 on human macrophages is mediated via . . .
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